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Insulin Resistance — The Common Root?
A 50-year index comparison: insulin resistance (USA & UK) against seven conditions — ADHD, Asthma, Type 2 Diabetes, Arthritis, IBD, Multiple Sclerosis, and Hypertension. All series indexed to 1975 = 1.0. The near-parallel rise across all conditions in both countries over 50 years is the pattern this series set out to test.
ADHD
0.94
USA · r
0.91
UK · r
Asthma
0.89
USA · r
0.85
UK · r
Type 2 Diabetes
0.98
USA · r
0.97
UK · r
Arthritis
0.87
USA · r
0.83
UK · r
IBD
0.93
USA · r
0.95
UK · r
Multiple Sclerosis
0.96
USA · r
0.97
UK · r
Hypertension
0.97
USA · r
0.95
UK · r
Range
0.83
Lowest r
0.98
Highest r
USA — All Conditions Indexed to 1975 = 1.0
Relative growth since 1975 | All series normalised for comparison
Insulin Resistance
ADHD
Asthma
T2DM
Arthritis
IBD
Multiple Sclerosis
Hypertension
UK — All Conditions Indexed to 1975 = 1.0
Relative growth since 1975 | All series normalised for comparison
Insulin Resistance
ADHD
Asthma
T2DM
Arthritis
IBD
Multiple Sclerosis
Hypertension
What the pattern shows: Across two countries, over 50 years, and across seven very different disease categories — neurological (ADHD), respiratory (asthma), metabolic (T2DM), musculoskeletal (arthritis), gastrointestinal (IBD), neuroinflammatory (MS), and cardiovascular (hypertension) — the correlation with rising insulin resistance is consistent, strong, and in some cases near-perfect. The lowest r value in this dataset is 0.83. In epidemiology, a correlation above 0.7 is considered strong. Every single condition in this series exceeds that threshold in both countries. This does not prove that insulin resistance causes these conditions individually — ecological correlation is not individual-level causation, and age, diagnostic expansion, and improved surveillance all contribute independently. But the pattern is there, it is consistent, and it demands explanation. The most plausible single mechanism connecting this breadth of conditions across this timescale is chronic systemic inflammation driven by hyperinsulinaemia.
What is r? Pearson correlation coefficient. 0 = no relationship | 1.0 = perfect parallel rise. Above 0.7 = strong. Population-level association — not proof of individual causation.
Data sources — full citations in individual condition charts 1–7
CDC ADHD |
CDC Asthma |
CDC Diabetes |
CDC Arthritis |
CDC IBD |
Wallin et al. MS prevalence |
NCHS Hypertension 2024 |
NHS Health Survey England |
IR prevalence data