The big issue could well be long term low grade inflammation from pesticide and herbicide residues in our bodies, from every day food. There is scientific evidence suggesting potential links, particularly regarding long-term low-level exposure and negative effects on the gut microbiome. This all makes sense because so many diseases are associated with inflammation. As I have already mentioned the GAPS method is rooted in the understanding that all disease comes from the gut, and since almost everyone eats mostly conventionally farmed foods, we are setting ourselves up for issues sooner or later.

Chronic Low-Grade Inflammation in US Adults Associated with Pesticide and Herbicide Exposure: A Metadata Summary of Published Studies

Published research indicates a significant association between exposure to pesticides and herbicides and the occurrence of chronic low-grade inflammation in adults residing in the United States. This persistent inflammatory state, often characterised by elevated levels of pro-inflammatory mediators, has been implicated as a contributing factor in the pathogenesis of various chronic diseases. Studies have identified several classes of pesticides and herbicides, including glyphosate, organophosphates, and neonicotinoids, as being linked to inflammatory responses in the human body. The health conditions associated with this exposure and subsequent inflammation encompass a range of disorders, including arthritis, respiratory diseases, neurological issues, metabolic syndrome, and cardiovascular problems. Given the widespread use of these chemicals in agriculture, residential areas, and public health initiatives across the US, understanding their potential to induce chronic low-grade inflammation is of paramount importance for public health and regulatory considerations.